| UNH | UnitedHealth Group Incorporated | NYSE | Healthcare Plans | $600.50 | 3.05% | 1.35% | 1.56% | $554,261,500,000.00 |
| JNJ | Johnson & Johnson | NYSE | Drug Manufacturers | $153.11 | 0.05% | -0.37% | 0.46% | $368,581,396,780.00 |
| NVO | Novo Nordisk A/S | NYSE | Biotechnology | $105.27 | 1.78% | -0.53% | 0.39% | $468,845,863,421.00 |
| MRK | Merck & Co., Inc. | NYSE | Drug Manufacturers | $97.44 | 0.47% | -1.76% | 1.72% | $246,721,017,328.00 |
| ABBV | AbbVie Inc. | NYSE | Drug Manufacturers | $167.76 | 0.51% | -2.32% | 0.99% | $296,767,440,000.00 |
| PFE | Pfizer Inc. | NYSE | Drug Manufacturers | $24.94 | -0.52% | -1.80% | 3.32% | $141,334,980,000.00 |
| TMO | Thermo Fisher Scientific Inc. | NYSE | Diagnostics & Research | $512.84 | 1.14% | -0.39% | 0.87% | $195,904,880,000.00 |
| RO.SW | Roche Holding AG | SIX | Drug Manufacturers | CHF264.40 | -1.42% | 0.49% | 1.12% | CHF199,110,800,000.00 |
| AZN | AstraZeneca PLC | NASDAQ | Drug Manufacturers | $63.20 | -1.08% | -0.61% | 1.17% | $195,920,000,000.00 |
| ABT | Abbott Laboratories | NYSE | Medical Devices | $115.93 | -0.65% | -0.12% | 0.84% | $201,075,476,892.00 |
| BMY | Bristol-Myers Squibb Company | NYSE | Drug Manufacturers | $57.88 | -1.25% | -1.48% | 1.05% | $117,380,640,000.00 |
| AMGN | Amgen Inc. | NASDAQ | Drug Manufacturers | $287.87 | 2.41% | -1.26% | 1.82% | $154,586,190,000.00 |
| MDT | Medtronic plc | NYSE | Medical Devices | $84.11 | -0.73% | 0.07% | 0.44% | $107,862,664,000.00 |
| SAN.PA | Sanofi | EURONEXT | Drug Manufacturers | EUR90.80 | -0.84% | -0.41% | 0.82% | EUR113,772,400,000.00 |
| GILD | Gilead Sciences, Inc. | NASDAQ | Drug Manufacturers | $88.63 | 0.59% | 0.65% | 1.13% | $110,521,610,000.00 |
| EL.PA | EssilorLuxottica Société anonyme | EURONEXT | Medical Instruments & Supplies | EUR233.80 | -0.76% | 0.65% | -0.23% | EUR105,696,829,582.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Biotechnology | $451.23 | 0.62% | -3.19% | 1.73% | $116,417,340,000.00 |
| GSK | GSK plc | NYSE | Drug Manufacturers | $33.35 | -0.15% | -0.55% | 6.23% | $68,034,000,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Biotechnology | $36.94 | -0.94% | -8.71% | 0.91% | $14,221,900,000.00 |
| BAYN.DE | Bayer Aktiengesellschaft | XETRA | Drug Manufacturers | EUR19.54 | -3.74% | 0.54% | -6.65% | EUR19,196,486,800.00 |
| BIIB | Biogen Inc. | NASDAQ | Drug Manufacturers | $156.00 | 0.63% | -1.09% | 1.81% | $22,729,200,000.00 |
| ALC | Alcon Inc. | NYSE | Medical Instruments & Supplies | $85.50 | 0.05% | -1.20% | 0.53% | $42,288,300,000.00 |
| BNTX | BioNTech SE | NASDAQ | Biotechnology | $102.14 | -3.46% | -1.56% | -1.52% | $24,487,018,269.00 |
| VEEV | Veeva Systems Inc. | NYSE | Health Information Services | $210.63 | -0.22% | 0.37% | 1.01% | $34,060,556,040.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Biotechnology | $194.26 | -0.38% | -0.64% | -0.29% | $20,572,909,097.00 |
| GMAB | Genmab A/S | NASDAQ | Biotechnology | $20.45 | -0.20% | 0.09% | 0.47% | $1,329,164,964.00 |
| BAX | Baxter International Inc. | NYSE | Medical Instruments & Supplies | $32.63 | 0.34% | -2.23% | 2.66% | $16,641,300,000.00 |
| ARGX | argenx SE | NASDAQ | Biotechnology | $591.82 | 0.55% | -1.18% | -0.44% | $35,560,983,066.00 |
| PHIA.AS | Koninklijke Philips N.V. | AMS | Medical Devices | EUR24.90 | 1.06% | -0.52% | 1.20% | EUR22,470,629,508.00 |
| ERF.PA | Eurofins Scientific SE | EURONEXT | Diagnostics & Research | EUR45.86 | 0.22% | 0.15% | 0.61% | EUR8,901,426,000.00 |
| TEVA | Teva Pharmaceutical Industries Limited | NYSE | Drug Manufacturers | $17.03 | 0.83% | -0.17% | 2.19% | $19,294,990,000.00 |
| SGFY | Signify Health, Inc. | NYSE | Health Information Services | $30.49 | 0.02% | 0.00% | 0.00% | $8,933,386,237.00 |
| OGN | Organon & Co. | NYSE | Drug Manufacturers | $14.73 | 0.96% | -0.49% | -0.50% | $3,792,945,540.00 |
| AMP.MI | Amplifon S.p.A. | MIL | Medical Instruments & Supplies | EUR23.23 | -2.35% | 2.81% | -1.24% | EUR5,257,629,290.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Biotechnology | $47.26 | 0.25% | 3.26% | 0.89% | $4,028,202,602.00 |
| TDOC | Teladoc Health, Inc. | NYSE | Health Information Services | $9.00 | 1.69% | 3.48% | 5.73% | $1,532,066,247.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $18.71 | 0.81% | -0.72% | -0.94% | $2,323,763,290.00 |
| PRVA | Privia Health Group, Inc. | NASDAQ | Health Information Services | $20.79 | -1.09% | 5.41% | -1.29% | $2,487,701,753.00 |
| GLPG | Galapagos NV | NASDAQ | Biotechnology | $25.64 | -1.00% | 3.17% | -1.11% | $3,259,183,678.00 |
| GLPG.AS | Galapagos NV | AMS | Biotechnology | EUR24.94 | -0.24% | 4.13% | 0.45% | EUR1,643,472,950.00 |
| GDRX | GoodRx Holdings, Inc. | NASDAQ | Health Information Services | $4.31 | 2.38% | -1.81% | -0.42% | $1,636,364,769.00 |
| TLRY | Tilray Brands, Inc. | NASDAQ | Drug Manufacturers | $1.29 | -1.53% | -6.04% | -1.81% | $1,129,323,828.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $7.30 | 1.96% | 4.07% | 1.12% | $1,510,406,500.00 |
| INMD | InMode Ltd. | NASDAQ | Medical Devices | $18.24 | 4.05% | -1.71% | 1.01% | $1,404,881,279.00 |
| MRUS | Merus N.V. | NASDAQ | Biotechnology | $42.93 | -0.85% | -3.52% | -1.74% | $2,930,149,371.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Biotechnology | $20.50 | 0.69% | -7.08% | -1.59% | $1,105,749,500.00 |
| GERN | Geron Corporation | NASDAQ | Biotechnology | $3.99 | 6.12% | -1.67% | -0.24% | $2,642,011,146.00 |
| NXGN | NextGen Healthcare, Inc. | NASDAQ | Health Information Services | $23.94 | 0.00% | 0.00% | 0.00% | $1,605,751,560.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Biotechnology | $26.05 | -7.39% | -2.52% | -4.91% | $1,249,774,800.00 |
| FAGR.BR | Fagron NV | EURONEXT | Drug Manufacturers | EUR18.18 | 0.00% | 0.95% | -0.11% | EUR1,336,263,051.00 |
| NVAX | Novavax, Inc. | NASDAQ | Biotechnology | $8.06 | 0.75% | -8.90% | -3.72% | $1,289,994,940.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Biotechnology | $0.27 | -5.48% | 2.90% | -8.24% | $344,837,768.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Biotechnology | EUR0.70 | -1.61% | -0.61% | 1.25% | EUR475,865,541.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Biotechnology | $8.48 | 2.42% | -5.67% | -1.54% | $716,859,581.00 |
| CLOV | Clover Health Investments, Corp. | NASDAQ | Healthcare Plans | $3.35 | 1.82% | -1.48% | 1.30% | $1,642,103,345.00 |
| SNDL | SNDL Inc. | NASDAQ | Drug Manufacturers | $1.96 | 0.51% | 1.02% | 0.52% | $519,688,120.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Biotechnology | $1.00 | -6.54% | -2.14% | 0.78% | $209,249,000.00 |
| NUTX | Nutex Health, Inc. | NASDAQ | Health Information Services | $30.33 | 6.46% | -11.54% | -6.45% | $154,683,909.00 |
| BNGO | Bionano Genomics, Inc. | NASDAQ | Diagnostics & Research | $0.21 | -8.96% | -2.42% | 0.12% | $17,981,178.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $3.97 | 0.25% | -3.96% | -2.83% | $111,717,773.00 |
| QURE | uniQure N.V. | NASDAQ | Biotechnology | $5.70 | -1.04% | -3.16% | -5.08% | $277,695,638.00 |
| AGEN | Agenus Inc. | NASDAQ | Biotechnology | $2.67 | 2.30% | -1.52% | 2.88% | $57,538,500.00 |
| SENS | Senseonics Holdings, Inc. | AMEX | Medical Devices | $0.32 | 5.77% | 2.67% | 2.11% | $197,010,921.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Biotechnology | $0.92 | 4.37% | 7.00% | -1.16% | $255,500,608.00 |
| IMMP | Immutep Limited | NASDAQ | Biotechnology | $1.96 | -3.45% | 2.59% | -0.50% | $2,379,241,363.00 |
| ZOM | Zomedica Corp. | AMEX | Drug Manufacturers | $0.13 | 3.47% | 2.94% | -0.15% | $128,569,396.00 |
| CGM.PA | Cegedim SA | EURONEXT | Health Information Services | EUR11.20 | 1.36% | 1.79% | 0.40% | EUR153,391,302.00 |
| GNFT | Genfit S.A. | NASDAQ | Biotechnology | $4.31 | 0.70% | 0.19% | -1.07% | $246,491,339.00 |
| ACB | Aurora Cannabis Inc. | NASDAQ | Drug Manufacturers | $4.24 | 0.95% | -0.62% | -1.30% | $201,071,794.00 |
| NVTA | Invitae Corporation | NYSE | Diagnostics & Research | $0.02 | 0.00% | 9.01% | 6.22% | $4,409,664.00 |
| ASXC | Asensus Surgical, Inc. | AMEX | Medical Devices | $0.35 | 0.55% | 1.72% | -0.65% | $94,738,736.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Biotechnology | $3.67 | 2.23% | 2.33% | 1.08% | $299,712,623.00 |
| TOI | The Oncology Institute, Inc. | NASDAQ | Medical Care Facilities | $0.13 | -11.87% | 0.00% | -0.59% | $9,984,381.60 |
| VXRT | Vaxart, Inc. | NASDAQ | Biotechnology | $0.61 | -1.97% | -1.27% | 1.28% | $138,245,862.00 |
| MDXH | MDxHealth SA | NASDAQ | Diagnostics & Research | $1.62 | 4.52% | -2.46% | 0.50% | $76,606,710.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Biotechnology | $7.50 | -0.27% | 8.01% | 0.00% | $569,790,000.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Biotechnology | $1.19 | -4.80% | 6.58% | -2.10% | $149,669,470.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Biotechnology | $16.70 | 0.00% | 0.00% | 0.24% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Biotechnology | $2.72 | -10.23% | 1.33% | -1.27% | $41,618,480.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Biotechnology | $0.19 | -27.34% | -5.27% | 7.31% | $118,032.18 |
| ALNOV.PA | Novacyt S.A. | EURONEXT | Medical Devices | EUR0.58 | -2.03% | 0.98% | -5.68% | EUR40,892,597.00 |
| NOVN | Novan, Inc. | NASDAQ | Biotechnology | $0.06 | 0.54% | 0.00% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Biotechnology | $2.20 | -1.79% | -3.72% | -3.68% | $7,087,973.20 |
| ALINS.PA | Intrasense SA | EURONEXT | Health Information Services | EUR0.28 | -0.71% | 9.51% | 2.14% | EUR14,613,255.00 |
| AMS | American Shared Hospital Services | AMEX | Medical Care Facilities | $3.02 | 0.67% | -1.56% | 1.26% | $19,575,640.00 |
| PEAR | Pear Therapeutics, Inc. | NASDAQ | Health Information Services | $0.00 | -4.00% | 0.00% | 0.00% | $4,050,252.52 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $2.40 | -0.83% | -9.49% | 0.75% | $24,513,808.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Biotechnology | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| BIOL | BIOLASE, Inc. | NASDAQ | Medical Devices | $0.01 | -0.71% | 0.00% | 11.13% | $232,067.45 |
| HCTI | Healthcare Triangle, Inc. | NASDAQ | Health Information Services | $1.15 | 1.77% | -2.34% | -2.22% | $6,516,173.70 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Biotechnology | $0.98 | 2.07% | -6.54% | 1.57% | $9,181,796.27 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Biotechnology | $10.90 | -2.15% | 9.78% | -0.22% | $60,454,201.00 |
| IBIO | iBio, Inc. | AMEX | Biotechnology | $2.17 | -7.26% | 0.00% | 11.81% | $18,733,610.00 |
| XCUR | Exicure, Inc. | NASDAQ | Biotechnology | $11.19 | 63.60% | 6.76% | -4.37% | $96,805,562.00 |
| OPGN | OpGen, Inc. | NASDAQ | Diagnostics & Research | $1.99 | 0.00% | -4.76% | -6.63% | $11,462,825.00 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Biotechnology | $0.71 | 0.00% | 0.00% | 0.00% | $4,227,641.99 |
| MLLAB.PA | Media Lab S.p.A. | EURONEXT | Health Information Services | EUR2.20 | 0.00% | 0.00% | 0.00% | EUR5,214,035.20 |
| NXNN | Nexeon MedSystems Inc. | PNK | Medical Devices | $0.00 | 0.00% | 0.00% | 0.00% | $177.58 |
| KIN | Kindred Biosciences, Inc. | NASDAQ | Drug Manufacturers | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Biotechnology | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
