| UNH | UnitedHealth Group Incorporated | NYSE | Healthcare Plans | $500.13 | 2.22% | -3.98% | 1.13% | $461,619,990,000.00 |
| JNJ | Johnson & Johnson | NYSE | Drug Manufacturers | $144.47 | 0.99% | -1.25% | -1.10% | $347,782,342,060.00 |
| NVO | Novo Nordisk A/S | NYSE | Biotechnology | $85.00 | 2.76% | 1.12% | 1.44% | $378,568,427,765.00 |
| MRK | Merck & Co., Inc. | NYSE | Drug Manufacturers | $98.05 | -0.79% | -0.94% | -0.27% | $248,265,555,717.00 |
| ABBV | AbbVie Inc. | NYSE | Drug Manufacturers | $175.58 | 2.21% | -0.90% | -0.71% | $310,601,020,000.00 |
| PFE | Pfizer Inc. | NYSE | Drug Manufacturers | $26.36 | 2.57% | -0.59% | -0.25% | $149,382,120,000.00 |
| TMO | Thermo Fisher Scientific Inc. | NYSE | Diagnostics & Research | $524.05 | 1.42% | -0.12% | -1.61% | $200,187,099,999.00 |
| RO.SW | Roche Holding AG | SIX | Drug Manufacturers | CHF261.20 | 0.93% | 1.88% | -1.11% | CHF197,672,600,000.00 |
| AZN | AstraZeneca PLC | NASDAQ | Drug Manufacturers | $65.35 | 2.22% | -0.30% | 1.86% | $202,584,999,999.00 |
| ABT | Abbott Laboratories | NYSE | Medical Devices | $114.23 | 1.41% | -1.01% | -1.86% | $198,126,901,797.00 |
| BMY | Bristol-Myers Squibb Company | NYSE | Drug Manufacturers | $57.33 | 1.97% | -2.33% | -0.87% | $116,265,240,000.00 |
| AMGN | Amgen Inc. | NASDAQ | Drug Manufacturers | $263.38 | -2.09% | -0.94% | -0.03% | $141,435,060,000.00 |
| MDT | Medtronic plc | NYSE | Medical Devices | $81.03 | 1.45% | -0.58% | -1.53% | $103,912,872,000.00 |
| SAN.PA | Sanofi | EURONEXT | Drug Manufacturers | EUR91.28 | 0.43% | -0.07% | -0.51% | EUR114,373,840,000.00 |
| GILD | Gilead Sciences, Inc. | NASDAQ | Drug Manufacturers | $92.57 | 1.81% | -0.02% | 4.15% | $115,434,789,999.00 |
| EL.PA | EssilorLuxottica Société anonyme | EURONEXT | Medical Instruments & Supplies | EUR231.20 | 0.39% | 1.94% | -0.18% | EUR104,521,415,737.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Biotechnology | $397.27 | 0.39% | -0.85% | 1.77% | $102,495,660,000.00 |
| GSK | GSK plc | NYSE | Drug Manufacturers | $33.60 | 1.39% | -1.03% | 1.19% | $68,544,000,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Biotechnology | $39.39 | 0.48% | 2.29% | -11.17% | $15,165,150,000.00 |
| BAYN.DE | Bayer Aktiengesellschaft | XETRA | Drug Manufacturers | EUR18.94 | 1.23% | -1.23% | -1.15% | EUR18,607,034,800.00 |
| BIIB | Biogen Inc. | NASDAQ | Drug Manufacturers | $146.47 | 0.57% | 0.70% | -1.01% | $21,340,679,000.00 |
| ALC | Alcon Inc. | NYSE | Medical Instruments & Supplies | $84.77 | 0.70% | -0.06% | -0.14% | $41,927,242,000.00 |
| BNTX | BioNTech SE | NASDAQ | Biotechnology | $113.08 | 2.09% | -0.52% | 0.20% | $27,109,771,156.00 |
| VEEV | Veeva Systems Inc. | NYSE | Health Information Services | $224.15 | 1.95% | -5.71% | 3.08% | $36,309,386,050.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Biotechnology | $176.45 | 0.09% | -1.36% | 2.02% | $18,686,759,035.00 |
| GMAB | Genmab A/S | NASDAQ | Biotechnology | $20.31 | 0.45% | -0.92% | 2.08% | $1,322,027,637.00 |
| BAX | Baxter International Inc. | NYSE | Medical Instruments & Supplies | $29.50 | 0.55% | -1.52% | 0.95% | $15,045,000,000.00 |
| ARGX | argenx SE | NASDAQ | Biotechnology | $623.82 | 0.10% | -1.03% | 0.38% | $37,483,783,002.00 |
| PHIA.AS | Koninklijke Philips N.V. | AMS | Medical Devices | EUR24.17 | 0.08% | -0.40% | -2.47% | EUR21,811,852,016.00 |
| ERF.PA | Eurofins Scientific SE | EURONEXT | Diagnostics & Research | EUR47.96 | 1.40% | 0.65% | 0.84% | EUR9,309,036,000.00 |
| TEVA | Teva Pharmaceutical Industries Limited | NYSE | Drug Manufacturers | $22.09 | 4.15% | 1.22% | -0.74% | $25,027,970,000.00 |
| SGFY | Signify Health, Inc. | NYSE | Health Information Services | $30.49 | 0.02% | 0.00% | 0.00% | $8,933,386,237.00 |
| OGN | Organon & Co. | NYSE | Drug Manufacturers | $14.58 | 0.28% | 3.57% | 0.75% | $3,754,320,840.00 |
| AMP.MI | Amplifon S.p.A. | MIL | Medical Instruments & Supplies | EUR24.80 | 2.35% | 2.09% | -2.91% | EUR5,612,966,268.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Biotechnology | $40.72 | 1.17% | -2.49% | 0.93% | $3,470,766,186.00 |
| TDOC | Teladoc Health, Inc. | NYSE | Health Information Services | $9.44 | 7.89% | -1.03% | 1.06% | $1,606,967,263.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $19.45 | 0.36% | -4.97% | 0.00% | $2,415,670,550.00 |
| PRVA | Privia Health Group, Inc. | NASDAQ | Health Information Services | $20.07 | 0.40% | -2.98% | 6.68% | $2,401,547,580.00 |
| GLPG | Galapagos NV | NASDAQ | Biotechnology | $26.76 | 1.87% | 1.87% | 1.70% | $1,763,405,619.00 |
| GLPG.AS | Galapagos NV | AMS | Biotechnology | EUR25.58 | 0.24% | -0.93% | -1.88% | EUR1,685,647,076.00 |
| GDRX | GoodRx Holdings, Inc. | NASDAQ | Health Information Services | $4.44 | -0.89% | -1.62% | -16.14% | $1,685,721,480.00 |
| TLRY | Tilray Brands, Inc. | NASDAQ | Drug Manufacturers | $1.26 | 10.53% | -1.56% | 0.00% | $1,103,060,483.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $7.57 | 4.41% | -0.51% | -0.39% | $1,566,270,850.00 |
| INMD | InMode Ltd. | NASDAQ | Medical Devices | $17.08 | -0.12% | -0.27% | 0.10% | $1,315,535,759.00 |
| MRUS | Merus N.V. | NASDAQ | Biotechnology | $41.85 | -1.27% | 0.70% | 1.98% | $2,856,434,922.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Biotechnology | $19.57 | 3.00% | 5.32% | -11.25% | $1,055,586,230.00 |
| GERN | Geron Corporation | NASDAQ | Biotechnology | $3.49 | -3.32% | 0.00% | -4.67% | $2,310,932,055.00 |
| NXGN | NextGen Healthcare, Inc. | NASDAQ | Health Information Services | $23.94 | 0.00% | 0.00% | 0.00% | $1,605,751,560.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Biotechnology | $2.35 | 4.91% | -0.35% | -4.09% | $112,743,600.00 |
| FAGR.BR | Fagron NV | EURONEXT | Drug Manufacturers | EUR18.12 | -1.52% | 0.22% | 0.42% | EUR1,337,733,087.00 |
| NVAX | Novavax, Inc. | NASDAQ | Biotechnology | $8.70 | 1.28% | -0.11% | 0.22% | $1,392,426,300.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Biotechnology | $0.26 | 0.00% | -8.19% | 3.13% | $327,218,320.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Biotechnology | EUR0.88 | 2.80% | 1.21% | -3.02% | EUR569,023,125.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Biotechnology | $8.63 | 1.05% | -2.73% | -2.05% | $729,539,880.00 |
| CLOV | Clover Health Investments, Corp. | NASDAQ | Healthcare Plans | $3.23 | 2.54% | -1.89% | -5.66% | $1,583,281,732.00 |
| SNDL | SNDL Inc. | NASDAQ | Drug Manufacturers | $1.80 | 5.26% | -1.08% | 0.00% | $477,264,600.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Biotechnology | $0.92 | -4.14% | -0.97% | -2.84% | $192,571,854.00 |
| NUTX | Nutex Health, Inc. | NASDAQ | Health Information Services | $29.38 | 1.80% | -7.26% | 6.33% | $149,838,881.00 |
| BNGO | Bionano Genomics, Inc. | NASDAQ | Diagnostics & Research | $0.20 | -1.02% | 0.08% | -1.83% | $16,744,650.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $1.84 | 0.55% | 0.25% | -2.65% | $51,778,514.00 |
| QURE | uniQure N.V. | NASDAQ | Biotechnology | $16.98 | 8.99% | 3.92% | 3.63% | $827,240,690.00 |
| AGEN | Agenus Inc. | NASDAQ | Biotechnology | $2.83 | 2.91% | -2.68% | -7.53% | $60,986,500.00 |
| SENS | Senseonics Holdings, Inc. | AMEX | Medical Devices | $0.46 | 6.31% | 12.66% | 5.98% | $285,488,879.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Biotechnology | $0.77 | 3.10% | -0.97% | 0.93% | $224,750,448.00 |
| IMMP | Immutep Limited | NASDAQ | Biotechnology | $2.03 | -3.79% | 10.80% | 1.66% | $2,464,214,269.00 |
| ZOM | Zomedica Corp. | AMEX | Drug Manufacturers | $0.13 | 4.68% | 0.32% | -0.98% | $122,787,693.00 |
| CGM.PA | Cegedim SA | EURONEXT | Health Information Services | EUR12.95 | -4.07% | 1.72% | -2.55% | EUR177,358,693.00 |
| GNFT | Genfit S.A. | NASDAQ | Biotechnology | $3.80 | 2.43% | -1.29% | -1.38% | $188,822,619.00 |
| ACB | Aurora Cannabis Inc. | NASDAQ | Drug Manufacturers | $4.27 | 4.91% | -2.25% | 0.00% | $202,494,472.00 |
| NVTA | Invitae Corporation | NYSE | Diagnostics & Research | $0.02 | 0.00% | 9.01% | 6.22% | $4,409,664.00 |
| ASXC | Asensus Surgical, Inc. | AMEX | Medical Devices | $0.35 | 0.55% | 1.72% | -0.65% | $94,738,736.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Biotechnology | $2.63 | 1.54% | -2.03% | -0.83% | $216,413,747.00 |
| TOI | The Oncology Institute, Inc. | NASDAQ | Medical Care Facilities | $0.21 | -8.25% | 0.00% | -12.74% | $15,867,765.00 |
| VXRT | Vaxart, Inc. | NASDAQ | Biotechnology | $0.62 | 3.27% | -3.93% | 0.35% | $140,929,806.00 |
| MDXH | MDxHealth SA | NASDAQ | Diagnostics & Research | $2.26 | 4.15% | 2.56% | -1.42% | $106,871,090.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Biotechnology | $5.49 | 3.39% | -4.59% | -3.01% | $417,086,280.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Biotechnology | $0.96 | -0.65% | -5.43% | 1.35% | $121,207,116.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Biotechnology | $16.70 | 0.00% | 0.00% | 0.00% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Biotechnology | $1.19 | 0.85% | -2.16% | 4.93% | $18,208,085.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Biotechnology | $0.61 | 8.84% | 1.10% | 0.86% | $37,993,988.00 |
| ALNOV.PA | Novacyt S.A. | EURONEXT | Medical Devices | EUR0.61 | -0.97% | 17.29% | -0.32% | EUR43,364,516.00 |
| NOVN | Novan, Inc. | NASDAQ | Biotechnology | $0.06 | 0.54% | 0.00% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Biotechnology | $1.73 | -1.14% | 0.56% | -9.47% | $5,617,310.00 |
| ALINS.PA | Intrasense SA | EURONEXT | Health Information Services | EUR0.25 | -5.22% | 1.48% | -0.69% | EUR13,303,824.00 |
| AMS | American Shared Hospital Services | AMEX | Medical Care Facilities | $3.32 | 0.91% | 7.69% | -1.56% | $21,520,240.00 |
| PEAR | Pear Therapeutics, Inc. | NASDAQ | Health Information Services | $0.00 | -4.00% | 0.00% | 0.00% | $4,050,252.52 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $2.25 | -4.26% | -3.35% | 1.20% | $22,981,695.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Biotechnology | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| BIOL | BIOLASE, Inc. | NASDAQ | Medical Devices | $0.01 | -0.71% | 0.00% | 11.13% | $232,067.45 |
| HCTI | Healthcare Triangle, Inc. | NASDAQ | Health Information Services | $0.80 | -4.86% | 0.28% | 2.40% | $4,530,157.28 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Biotechnology | $0.93 | 3.12% | 26.73% | -6.60% | $8,672,060.87 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Biotechnology | $8.91 | -2.09% | -2.69% | 3.95% | $72,425,086.00 |
| IBIO | iBio, Inc. | AMEX | Biotechnology | $2.49 | 1.63% | -2.99% | -0.39% | $21,496,170.00 |
| XCUR | Exicure, Inc. | NASDAQ | Biotechnology | $18.67 | 10.41% | 3.23% | 0.39% | $35,462,022.00 |
| OPGN | OpGen, Inc. | NASDAQ | Diagnostics & Research | $0.71 | -38.26% | 8.33% | -5.71% | $4,089,751.94 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Biotechnology | $0.74 | 0.00% | 0.00% | 0.00% | $4,375,461.64 |
| MLLAB.PA | Media Lab S.p.A. | EURONEXT | Health Information Services | EUR2.22 | 0.00% | 0.00% | 0.00% | EUR5,261,435.52 |
| NXNN | Nexeon MedSystems Inc. | PNK | Medical Devices | $0.00 | 0.00% | 0.00% | 0.00% | $177.58 |
| KIN | Kindred Biosciences, Inc. | NASDAQ | Drug Manufacturers | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Biotechnology | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
