| UNH | UnitedHealth Group Incorporated | NYSE | Healthcare Plans | $513.00 | 1.31% | 1.11% | -0.98% | $473,499,000,000.00 |
| JNJ | Johnson & Johnson | NYSE | Drug Manufacturers | $144.19 | 0.08% | 0.44% | -0.62% | $347,108,298,620.00 |
| NVO | Novo Nordisk A/S | NYSE | Biotechnology | $87.65 | 0.18% | -0.18% | 1.43% | $390,370,855,218.00 |
| MRK | Merck & Co., Inc. | NYSE | Drug Manufacturers | $99.14 | -0.20% | 0.28% | -0.20% | $251,025,468,575.00 |
| ABBV | AbbVie Inc. | NYSE | Drug Manufacturers | $181.22 | 0.87% | 1.77% | 0.79% | $320,578,180,000.00 |
| PFE | Pfizer Inc. | NYSE | Drug Manufacturers | $26.59 | -0.41% | 1.33% | 1.62% | $150,685,530,000.00 |
| TMO | Thermo Fisher Scientific Inc. | NYSE | Diagnostics & Research | $532.02 | 1.47% | 0.98% | 2.61% | $203,231,640,000.00 |
| RO.SW | Roche Holding AG | SIX | Drug Manufacturers | CHF272.40 | -0.58% | 1.64% | -0.92% | CHF205,023,400,000.00 |
| AZN | AstraZeneca PLC | NASDAQ | Drug Manufacturers | $66.25 | -0.30% | 1.18% | 0.24% | $410,750,000,000.00 |
| ABT | Abbott Laboratories | NYSE | Medical Devices | $113.83 | -0.10% | 0.27% | 0.51% | $197,433,119,422.00 |
| BMY | Bristol-Myers Squibb Company | NYSE | Drug Manufacturers | $56.57 | 0.41% | 0.58% | 3.06% | $114,723,960,000.00 |
| AMGN | Amgen Inc. | NASDAQ | Drug Manufacturers | $261.22 | 0.47% | 0.34% | 0.82% | $140,275,140,000.00 |
| MDT | Medtronic plc | NYSE | Medical Devices | $80.95 | 0.56% | 0.88% | -1.16% | $103,810,280,000.00 |
| SAN.PA | Sanofi | EURONEXT | Drug Manufacturers | EUR92.87 | -1.31% | 0.43% | -0.86% | EUR116,366,110,000.00 |
| GILD | Gilead Sciences, Inc. | NASDAQ | Drug Manufacturers | $91.41 | -0.85% | 0.84% | 0.14% | $113,988,270,000.00 |
| EL.PA | EssilorLuxottica Société anonyme | EURONEXT | Medical Instruments & Supplies | EUR230.20 | -1.20% | 0.39% | 2.05% | EUR104,069,333,489.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Biotechnology | $407.11 | -0.11% | 3.42% | -3.20% | $105,034,380,000.00 |
| GSK | GSK plc | NYSE | Drug Manufacturers | $33.47 | -1.50% | 0.59% | 0.54% | $68,278,800,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Biotechnology | $42.18 | -0.17% | 1.02% | -4.14% | $16,239,300,000.00 |
| BAYN.DE | Bayer Aktiengesellschaft | XETRA | Drug Manufacturers | EUR18.99 | -1.96% | -0.26% | 0.64% | EUR18,656,155,800.00 |
| BIIB | Biogen Inc. | NASDAQ | Drug Manufacturers | $152.21 | 1.66% | 2.32% | -1.01% | $22,176,997,000.00 |
| ALC | Alcon Inc. | NYSE | Medical Instruments & Supplies | $84.06 | 0.15% | 0.20% | -0.85% | $41,576,076,000.00 |
| BNTX | BioNTech SE | NASDAQ | Biotechnology | $115.79 | 0.34% | 1.18% | 3.52% | $27,759,465,884.00 |
| VEEV | Veeva Systems Inc. | NYSE | Health Information Services | $213.03 | 1.04% | 1.04% | -1.00% | $34,508,090,610.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Biotechnology | $184.71 | 0.39% | -0.26% | 0.77% | $1,504,732,768.00 |
| GMAB | Genmab A/S | NASDAQ | Biotechnology | $21.47 | 1.51% | 0.24% | -0.05% | $13,930,764,842.00 |
| BAX | Baxter International Inc. | NYSE | Medical Instruments & Supplies | $29.50 | 0.75% | -0.41% | -0.58% | $15,045,000,000.00 |
| ARGX | argenx SE | NASDAQ | Biotechnology | $621.29 | -0.56% | 0.43% | 0.89% | $37,331,761,632.00 |
| PHIA.AS | Koninklijke Philips N.V. | AMS | Medical Devices | EUR24.37 | 0.45% | 0.08% | -0.61% | EUR21,992,339,000.00 |
| ERF.PA | Eurofins Scientific SE | EURONEXT | Diagnostics & Research | EUR48.57 | -0.47% | 1.40% | -0.31% | EUR9,427,437,000.00 |
| TEVA | Teva Pharmaceutical Industries Limited | NYSE | Drug Manufacturers | $21.24 | -0.75% | 0.95% | 2.31% | $24,064,920,000.00 |
| SGFY | Signify Health, Inc. | NYSE | Health Information Services | $30.49 | 0.02% | 0.00% | 0.00% | $8,933,386,237.00 |
| OGN | Organon & Co. | NYSE | Drug Manufacturers | $15.44 | 3.21% | 1.31% | -2.28% | $3,975,769,120.00 |
| AMP.MI | Amplifon S.p.A. | MIL | Medical Instruments & Supplies | EUR24.36 | -2.33% | 0.69% | 0.04% | EUR5,513,381,382.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Biotechnology | $41.02 | -1.16% | -0.83% | 0.00% | $3,496,336,664.00 |
| TDOC | Teladoc Health, Inc. | NYSE | Health Information Services | $9.52 | -0.31% | -2.98% | 0.11% | $1,620,585,630.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $19.79 | 0.61% | 1.28% | -2.00% | $2,457,898,210.00 |
| PRVA | Privia Health Group, Inc. | NASDAQ | Health Information Services | $19.96 | 1.32% | -0.60% | 2.23% | $2,388,385,137.00 |
| GLPG | Galapagos NV | NASDAQ | Biotechnology | $28.42 | 0.89% | 1.88% | -1.00% | $1,872,794,757.00 |
| GLPG.AS | Galapagos NV | AMS | Biotechnology | EUR27.38 | -0.07% | 0.24% | 0.78% | EUR1,804,261,803.00 |
| GDRX | GoodRx Holdings, Inc. | NASDAQ | Health Information Services | $4.45 | -2.84% | 3.20% | 0.24% | $1,689,518,150.00 |
| TLRY | Tilray Brands, Inc. | NASDAQ | Drug Manufacturers | $1.45 | -2.03% | 6.72% | 0.77% | $1,269,395,000.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $7.70 | -2.16% | 2.77% | 2.12% | $1,593,168,500.00 |
| INMD | InMode Ltd. | NASDAQ | Medical Devices | $17.01 | 0.06% | -0.99% | 0.00% | $1,310,144,220.00 |
| MRUS | Merus N.V. | NASDAQ | Biotechnology | $43.16 | 1.65% | 1.56% | -1.70% | $2,945,847,819.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Biotechnology | $18.53 | -0.59% | -4.30% | -1.96% | $999,489,670.00 |
| GERN | Geron Corporation | NASDAQ | Biotechnology | $3.57 | -1.65% | -4.30% | 1.61% | $2,363,904,709.00 |
| NXGN | NextGen Healthcare, Inc. | NASDAQ | Health Information Services | $23.94 | 0.00% | 0.00% | 0.00% | $1,605,751,560.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Biotechnology | $2.89 | 5.09% | 2.99% | -0.81% | $138,650,640.00 |
| FAGR.BR | Fagron NV | EURONEXT | Drug Manufacturers | EUR16.58 | -0.72% | -1.52% | 0.00% | EUR1,218,660,142.00 |
| NVAX | Novavax, Inc. | NASDAQ | Biotechnology | $8.85 | 3.27% | -0.69% | 2.56% | $1,416,433,650.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Biotechnology | $0.28 | 0.00% | -4.34% | -1.13% | $352,263,106.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Biotechnology | EUR0.95 | -2.37% | 2.80% | -0.49% | EUR611,029,375.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Biotechnology | $12.35 | 0.41% | 25.34% | 8.85% | $1,044,011,300.00 |
| CLOV | Clover Health Investments, Corp. | NASDAQ | Healthcare Plans | $3.29 | 4.44% | 0.62% | 3.14% | $1,612,692,538.00 |
| SNDL | SNDL Inc. | NASDAQ | Drug Manufacturers | $1.91 | 1.06% | 1.65% | 3.13% | $506,430,770.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Biotechnology | $1.10 | 14.58% | -2.99% | 0.98% | $230,173,900.00 |
| NUTX | Nutex Health, Inc. | NASDAQ | Health Information Services | $33.88 | -1.57% | 8.13% | 3.41% | $172,789,016.00 |
| BNGO | Bionano Genomics, Inc. | NASDAQ | Diagnostics & Research | $0.32 | 2.16% | -1.61% | -1.49% | $27,195,029.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $1.96 | 8.29% | -1.65% | 0.50% | $55,155,374.00 |
| QURE | uniQure N.V. | NASDAQ | Biotechnology | $17.94 | 2.22% | 2.77% | -4.12% | $874,010,482.00 |
| AGEN | Agenus Inc. | NASDAQ | Biotechnology | $3.27 | 6.17% | -4.90% | 0.00% | $70,468,500.00 |
| SENS | Senseonics Holdings, Inc. | AMEX | Medical Devices | $0.50 | 6.45% | -0.69% | 5.90% | $310,635,246.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Biotechnology | $0.89 | -9.39% | -2.80% | -4.43% | $259,640,031.00 |
| IMMP | Immutep Limited | NASDAQ | Biotechnology | $2.18 | -0.91% | -1.49% | 1.00% | $264,629,906.00 |
| ZOM | Zomedica Corp. | AMEX | Drug Manufacturers | $0.15 | 3.45% | -3.46% | -0.79% | $143,954,606.00 |
| CGM.PA | Cegedim SA | EURONEXT | Health Information Services | EUR13.00 | -2.26% | -4.07% | -1.34% | EUR178,043,476.00 |
| GNFT | Genfit S.A. | NASDAQ | Biotechnology | $3.74 | -1.32% | -0.78% | -1.84% | $185,841,209.00 |
| ACB | Aurora Cannabis Inc. | NASDAQ | Drug Manufacturers | $4.70 | 3.75% | -0.92% | -1.65% | $222,886,187.00 |
| NVTA | Invitae Corporation | NYSE | Diagnostics & Research | $0.02 | 0.00% | 9.01% | 6.22% | $4,409,664.00 |
| ASXC | Asensus Surgical, Inc. | AMEX | Medical Devices | $0.35 | 0.55% | 1.72% | -0.65% | $94,738,736.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Biotechnology | $2.76 | 0.36% | 0.75% | -1.37% | $225,396,959.00 |
| TOI | The Oncology Institute, Inc. | NASDAQ | Medical Care Facilities | $0.32 | 3.26% | 0.94% | 5.32% | $24,175,495.00 |
| VXRT | Vaxart, Inc. | NASDAQ | Biotechnology | $0.84 | 14.71% | 0.37% | 0.00% | $190,469,044.00 |
| MDXH | MDxHealth SA | NASDAQ | Diagnostics & Research | $2.32 | -0.43% | -3.56% | -5.99% | $109,708,375.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Biotechnology | $5.51 | 0.73% | -2.93% | 4.01% | $418,605,720.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Biotechnology | $1.01 | 2.12% | 0.00% | 0.00% | $127,030,390.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Biotechnology | $16.70 | 0.00% | 0.00% | 0.00% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Biotechnology | $1.36 | -0.73% | 0.00% | -5.96% | $20,809,240.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Biotechnology | $0.31 | 0.36% | -19.22% | 22.33% | $19,257,907.00 |
| ALNOV.PA | Novacyt S.A. | EURONEXT | Medical Devices | EUR0.67 | 8.59% | -0.97% | -1.99% | EUR47,319,586.00 |
| NOVN | Novan, Inc. | NASDAQ | Biotechnology | $0.06 | 0.54% | 0.00% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Biotechnology | $1.88 | -1.57% | 1.76% | 1.86% | $6,104,360.00 |
| ALINS.PA | Intrasense SA | EURONEXT | Health Information Services | EUR0.26 | 2.38% | -5.22% | 4.44% | EUR13,513,333.00 |
| AMS | American Shared Hospital Services | AMEX | Medical Care Facilities | $3.10 | -0.96% | 1.24% | -0.33% | $20,094,200.00 |
| PEAR | Pear Therapeutics, Inc. | NASDAQ | Health Information Services | $0.00 | -4.00% | 0.00% | 0.00% | $4,050,252.52 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Biotechnology | $1.63 | -1.81% | -3.75% | 3.70% | $16,648,961.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Biotechnology | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| BIOL | BIOLASE, Inc. | NASDAQ | Medical Devices | $0.01 | -0.71% | 0.00% | 11.13% | $232,067.45 |
| HCTI | Healthcare Triangle, Inc. | NASDAQ | Health Information Services | $1.20 | 26.72% | -3.98% | -0.88% | $6,799,485.60 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Biotechnology | $1.15 | 3.60% | 0.70% | -0.05% | $10,775,656.00 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Biotechnology | $8.39 | -1.87% | 2.25% | -2.21% | $68,198,257.00 |
| IBIO | iBio, Inc. | AMEX | Biotechnology | $2.45 | -0.41% | -2.48% | 3.24% | $21,150,850.00 |
| XCUR | Exicure, Inc. | NASDAQ | Biotechnology | $14.36 | -2.11% | 4.49% | 36.30% | $27,275,556.00 |
| OPGN | OpGen, Inc. | NASDAQ | Diagnostics & Research | $0.75 | 10.91% | 7.74% | 0.51% | $4,344,353.40 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Biotechnology | $0.74 | 0.00% | 0.34% | 0.00% | $4,405,025.57 |
| MLLAB.PA | Media Lab S.p.A. | EURONEXT | Health Information Services | EUR2.22 | 0.00% | 0.00% | 0.00% | EUR5,261,435.52 |
| NXNN | Nexeon MedSystems Inc. | PNK | Medical Devices | $0.00 | 0.00% | 0.00% | 0.00% | $177.58 |
| KIN | Kindred Biosciences, Inc. | NASDAQ | Drug Manufacturers | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Biotechnology | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
