| NVO | Novo Nordisk A/S | NYSE | Healthcare | $126.73 | -0.10% | -0.73% | -0.18% | $567,640,186,000.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Healthcare | $495.26 | 0.43% | -0.32% | -0.46% | $129,655,130,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Healthcare | $122.11 | 0.23% | 0.76% | -1.52% | $46,271,660,000.00 |
| BNTX | BioNTech SE | NASDAQ | Healthcare | $85.94 | 1.05% | -0.36% | -3.87% | $20,671,522,124.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Healthcare | $162.53 | -0.79% | 1.56% | 6.57% | $22,232,336,515.00 |
| GMAB | Genmab A/S | NASDAQ | Healthcare | $28.38 | 0.71% | 0.60% | -0.85% | $1,856,567,246.00 |
| ARGX | argenx SE | NASDAQ | Healthcare | $494.89 | 3.96% | -0.47% | 0.55% | $29,316,337,922.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Healthcare | $57.92 | -0.97% | -1.08% | 0.98% | $4,735,500,103.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Healthcare | $28.19 | -3.79% | -2.37% | 0.51% | $3,575,265,000.00 |
| GLPG | Galapagos NV | NASDAQ | Healthcare | $27.43 | 0.40% | 2.00% | -0.08% | $1,798,331,067.00 |
| GLPG.AS | Galapagos NV | AMS | Healthcare | EUR25.14 | 0.24% | 0.49% | -0.17% | EUR1,655,334,423.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Healthcare | $7.86 | 2.21% | -0.95% | -5.83% | $1,574,205,321.00 |
| MRUS | Merus N.V. | NASDAQ | Healthcare | $54.19 | -1.10% | -2.40% | -2.04% | $3,160,427,484.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Healthcare | $17.40 | -1.64% | 0.33% | 12.90% | $933,181,699.00 |
| GERN | Geron Corporation | NASDAQ | Healthcare | $4.66 | 7.13% | -3.05% | -2.12% | $2,754,947,603.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Healthcare | $14.92 | 15.30% | -2.84% | -1.40% | $565,463,150.00 |
| NVAX | Novavax, Inc. | NASDAQ | Healthcare | $17.11 | 0.41% | -2.16% | -4.86% | $2,377,172,840.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Healthcare | $0.38 | -5.23% | -0.56% | -2.09% | $460,051,292.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Healthcare | EUR0.77 | -0.13% | 1.09% | -0.93% | EUR501,850,947.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Healthcare | $6.74 | -3.71% | 3.86% | -1.83% | $562,406,021.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Healthcare | $1.37 | 0.00% | 1.40% | 2.38% | $263,880,830.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Healthcare | $11.32 | 0.71% | 0.91% | -3.85% | $260,864,934.00 |
| QURE | uniQure N.V. | NASDAQ | Healthcare | $8.34 | -3.25% | -7.33% | -2.40% | $405,946,038.00 |
| AGEN | Agenus Inc. | NASDAQ | Healthcare | $6.56 | 9.15% | 3.08% | -1.57% | $133,752,615.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Healthcare | $1.64 | 0.61% | -3.68% | -1.91% | $412,858,380.00 |
| IMMP | Immutep Limited | NASDAQ | Healthcare | $2.17 | 1.40% | -3.38% | -7.58% | $2,573,301,260.00 |
| GNFT | Genfit S.A. | NASDAQ | Healthcare | $4.01 | -8.86% | 2.40% | -6.56% | $199,280,887.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Healthcare | $1.88 | -1.05% | -2.13% | -2.70% | $154,976,796.00 |
| VXRT | Vaxart, Inc. | NASDAQ | Healthcare | $0.70 | 1.19% | -3.26% | -4.20% | $116,057,627.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Healthcare | $3.07 | -3.76% | -3.64% | -2.57% | $233,844,932.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Healthcare | $1.47 | 4.26% | -0.71% | 1.59% | $177,114,442.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Healthcare | $16.70 | 0.00% | 0.00% | 0.24% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Healthcare | $5.13 | -0.77% | -1.25% | -1.72% | $78,121,994.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Healthcare | $0.55 | -0.22% | -2.44% | -2.63% | $43,925,439.00 |
| NOVN | Novan, Inc. | NASDAQ | Healthcare | $0.06 | 0.54% | -1.48% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Healthcare | $5.42 | 3.44% | 5.18% | -1.54% | $17,846,806.00 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Healthcare | $4.15 | 2.22% | -1.04% | -3.76% | $21,579,089.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Healthcare | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Healthcare | $1.28 | -3.76% | -1.67% | 0.27% | $211,276,139.00 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Healthcare | $11.52 | -4.00% | 7.99% | 4.26% | $10,140,695.00 |
| IBIO | iBio, Inc. | AMEX | Healthcare | $2.25 | 0.00% | 0.94% | 2.00% | $8,354,250.00 |
| XCUR | Exicure, Inc. | NASDAQ | Healthcare | $0.48 | 10.80% | -5.36% | 3.61% | $4,065,912.66 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Healthcare | $0.98 | 4.26% | 0.00% | 2.23% | $5,558,018.84 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Healthcare | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
