| NVO | Novo Nordisk A/S | NYSE | Healthcare | $87.37 | -1.72% | -0.08% | -0.53% | $389,123,806,280.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Healthcare | $408.18 | 1.66% | 0.30% | -3.19% | $105,310,440,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Healthcare | $40.27 | 1.72% | -0.97% | -8.71% | $15,503,950,000.00 |
| BNTX | BioNTech SE | NASDAQ | Healthcare | $114.13 | 1.18% | 1.36% | -1.56% | $27,361,497,895.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Healthcare | $181.62 | 2.19% | 1.24% | -0.64% | $1,479,560,204.00 |
| GMAB | Genmab A/S | NASDAQ | Healthcare | $20.47 | -0.87% | -1.42% | 0.09% | $13,281,916,922.00 |
| ARGX | argenx SE | NASDAQ | Healthcare | $629.99 | 0.52% | -0.46% | -1.18% | $37,854,522,865.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Healthcare | $40.94 | 1.14% | -2.73% | 3.26% | $3,489,517,870.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Healthcare | $19.63 | -0.76% | -0.50% | -0.72% | $2,438,026,370.00 |
| GLPG | Galapagos NV | NASDAQ | Healthcare | $27.21 | 0.52% | 0.30% | 3.17% | $1,793,059,301.00 |
| GLPG.AS | Galapagos NV | AMS | Healthcare | EUR25.92 | -0.15% | -1.94% | -0.84% | EUR1,708,052,080.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Healthcare | $7.67 | -0.78% | -0.40% | 4.07% | $1,586,961,350.00 |
| MRUS | Merus N.V. | NASDAQ | Healthcare | $42.41 | -0.93% | 3.68% | -3.52% | $2,894,657,229.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Healthcare | $18.83 | -0.58% | -3.72% | -7.08% | $1,015,671,369.00 |
| GERN | Geron Corporation | NASDAQ | Healthcare | $3.34 | 0.00% | -3.02% | -1.67% | $2,211,608,327.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Healthcare | $2.34 | -3.70% | -1.43% | -2.52% | $112,263,840.00 |
| NVAX | Novavax, Inc. | NASDAQ | Healthcare | $8.51 | -1.73% | 1.22% | -8.90% | $1,362,016,990.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Healthcare | $0.26 | -1.92% | -2.53% | 2.90% | $327,344,173.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Healthcare | EUR0.89 | -0.56% | 1.88% | -0.89% | EUR577,101,250.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Healthcare | $10.87 | -5.64% | -1.63% | -5.67% | $918,899,015.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Healthcare | $0.91 | 1.81% | 1.00% | -2.14% | $189,956,242.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Healthcare | $1.83 | 1.67% | -7.94% | -3.96% | $51,497,109.00 |
| QURE | uniQure N.V. | NASDAQ | Healthcare | $17.35 | -2.96% | 2.80% | -3.16% | $845,266,547.00 |
| AGEN | Agenus Inc. | NASDAQ | Healthcare | $2.75 | 1.85% | -1.61% | -1.52% | $59,262,500.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Healthcare | $0.72 | -5.45% | -0.30% | 7.00% | $208,466,708.00 |
| IMMP | Immutep Limited | NASDAQ | Healthcare | $1.95 | -1.52% | -1.80% | 2.59% | $236,710,237.00 |
| GNFT | Genfit S.A. | NASDAQ | Healthcare | $3.67 | -0.27% | 1.60% | 0.19% | $182,362,898.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Healthcare | $2.67 | -0.37% | -13.46% | 2.33% | $218,047,058.00 |
| VXRT | Vaxart, Inc. | NASDAQ | Healthcare | $0.61 | 1.48% | -1.27% | -1.27% | $138,473,315.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Healthcare | $5.44 | 2.45% | -2.86% | 8.01% | $413,287,680.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Healthcare | $1.03 | 1.98% | -2.61% | 6.58% | $129,545,843.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Healthcare | $16.70 | 0.00% | 0.00% | 0.00% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Healthcare | $1.24 | 3.33% | -0.46% | 1.33% | $18,743,617.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Healthcare | $0.39 | -6.00% | -1.72% | -5.27% | $23,935,715.00 |
| NOVN | Novan, Inc. | NASDAQ | Healthcare | $0.06 | 0.54% | 0.00% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Healthcare | $1.75 | -1.69% | 7.78% | -3.72% | $5,682,250.00 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Healthcare | $1.63 | -1.81% | -3.75% | 3.70% | $16,648,961.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Healthcare | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Healthcare | $1.03 | 3.00% | -4.03% | -6.54% | $9,651,240.08 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Healthcare | $8.81 | -3.50% | -0.65% | 9.78% | $71,612,234.00 |
| IBIO | iBio, Inc. | AMEX | Healthcare | $2.42 | 2.54% | -7.97% | 0.00% | $20,891,860.00 |
| XCUR | Exicure, Inc. | NASDAQ | Healthcare | $17.18 | -10.24% | -0.52% | 6.76% | $32,631,898.00 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Healthcare | $0.74 | 0.00% | 0.00% | 0.00% | $4,375,461.64 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Healthcare | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
