| NVO | Novo Nordisk A/S | NYSE | Healthcare | $87.65 | 0.18% | -0.18% | 1.43% | $390,370,855,218.00 |
| VRTX | Vertex Pharmaceuticals Incorporated | NASDAQ | Healthcare | $407.11 | -0.11% | 3.42% | -3.20% | $105,034,380,000.00 |
| MRNA | Moderna, Inc. | NASDAQ | Healthcare | $42.18 | -0.17% | 1.02% | -4.14% | $16,239,300,000.00 |
| BNTX | BioNTech SE | NASDAQ | Healthcare | $115.79 | 0.34% | 1.18% | 3.52% | $27,759,465,884.00 |
| BGNE | BeiGene, Ltd. | NASDAQ | Healthcare | $184.71 | 0.39% | -0.26% | 0.77% | $1,504,732,768.00 |
| GMAB | Genmab A/S | NASDAQ | Healthcare | $21.47 | 1.51% | 0.24% | -0.05% | $13,930,764,842.00 |
| ARGX | argenx SE | NASDAQ | Healthcare | $621.29 | -0.56% | 0.43% | 0.89% | $37,331,761,632.00 |
| CRSP | CRISPR Therapeutics AG | NASDAQ | Healthcare | $41.02 | -1.16% | -0.83% | 0.00% | $3,496,336,664.00 |
| ARWR | Arrowhead Pharmaceuticals, Inc. | NASDAQ | Healthcare | $19.79 | 0.61% | 1.28% | -2.00% | $2,457,898,210.00 |
| GLPG | Galapagos NV | NASDAQ | Healthcare | $28.42 | 0.89% | 1.88% | -1.00% | $1,872,794,757.00 |
| GLPG.AS | Galapagos NV | AMS | Healthcare | EUR27.38 | -0.07% | 0.24% | 0.78% | EUR1,804,261,803.00 |
| BCRX | BioCryst Pharmaceuticals, Inc. | NASDAQ | Healthcare | $7.70 | -2.16% | 2.77% | 2.12% | $1,593,168,500.00 |
| MRUS | Merus N.V. | NASDAQ | Healthcare | $43.16 | 1.65% | 1.56% | -1.70% | $2,945,847,819.00 |
| PHVS | Pharvaris N.V. | NASDAQ | Healthcare | $18.53 | -0.59% | -4.30% | -1.96% | $999,489,670.00 |
| GERN | Geron Corporation | NASDAQ | Healthcare | $3.57 | -1.65% | -4.30% | 1.61% | $2,363,904,709.00 |
| SAVA | Cassava Sciences, Inc. | NASDAQ | Healthcare | $2.89 | 5.09% | 2.99% | -0.81% | $138,650,640.00 |
| NVAX | Novavax, Inc. | NASDAQ | Healthcare | $8.85 | 3.27% | -0.69% | 2.56% | $1,416,433,650.00 |
| NWBO | Northwest Biotherapeutics, Inc. | PNK | Healthcare | $0.28 | 0.00% | -4.34% | -1.13% | $352,263,106.00 |
| PHARM.AS | Pharming Group N.V. | AMS | Healthcare | EUR0.95 | -2.37% | 2.80% | -0.49% | EUR611,029,375.00 |
| AVXL | Anavex Life Sciences Corp. | NASDAQ | Healthcare | $12.35 | 0.41% | 25.34% | 8.85% | $1,044,011,300.00 |
| NKTR | Nektar Therapeutics | NASDAQ | Healthcare | $1.10 | 14.58% | -2.99% | 0.98% | $230,173,900.00 |
| INO | Inovio Pharmaceuticals, Inc. | NASDAQ | Healthcare | $1.96 | 8.29% | -1.65% | 0.50% | $55,155,374.00 |
| QURE | uniQure N.V. | NASDAQ | Healthcare | $17.94 | 2.22% | 2.77% | -4.12% | $874,010,482.00 |
| AGEN | Agenus Inc. | NASDAQ | Healthcare | $3.27 | 6.17% | -4.90% | 0.00% | $70,468,500.00 |
| OCGN | Ocugen, Inc. | NASDAQ | Healthcare | $0.89 | -9.39% | -2.80% | -4.43% | $259,640,031.00 |
| IMMP | Immutep Limited | NASDAQ | Healthcare | $2.18 | -0.91% | -1.49% | 1.00% | $264,629,906.00 |
| GNFT | Genfit S.A. | NASDAQ | Healthcare | $3.74 | -1.32% | -0.78% | -1.84% | $185,841,209.00 |
| PRQR | ProQR Therapeutics N.V. | NASDAQ | Healthcare | $2.76 | 0.36% | 0.75% | -1.37% | $225,396,959.00 |
| VXRT | Vaxart, Inc. | NASDAQ | Healthcare | $0.84 | 14.71% | 0.37% | 0.00% | $190,469,044.00 |
| CDXC | ChromaDex Corporation | NASDAQ | Healthcare | $5.51 | 0.73% | -2.93% | 4.01% | $418,605,720.00 |
| ATOS | Atossa Therapeutics, Inc. | NASDAQ | Healthcare | $1.01 | 2.12% | 0.00% | 0.00% | $127,030,390.00 |
| ORTX | Orchard Therapeutics plc | NASDAQ | Healthcare | $16.70 | 0.00% | 0.00% | 0.00% | $381,408,895.00 |
| AFMD | Affimed N.V. | NASDAQ | Healthcare | $1.36 | -0.73% | 0.00% | -5.96% | $20,809,240.00 |
| TNXP | Tonix Pharmaceuticals Holding Corp. | NASDAQ | Healthcare | $0.31 | 0.36% | -19.22% | 22.33% | $19,257,907.00 |
| NOVN | Novan, Inc. | NASDAQ | Healthcare | $0.06 | 0.54% | 0.00% | 0.00% | $1,462,495.22 |
| EDSA | Edesa Biotech, Inc. | NASDAQ | Healthcare | $1.88 | -1.57% | 1.76% | 1.86% | $6,104,360.00 |
| NRBO | NeuroBo Pharmaceuticals, Inc. | NASDAQ | Healthcare | $1.63 | -1.81% | -3.75% | 3.70% | $16,648,961.00 |
| CYAD | Celyad Oncology SA | NASDAQ | Healthcare | $0.47 | -9.62% | 0.00% | 0.00% | $10,619,159.00 |
| JAGX | Jaguar Health, Inc. | NASDAQ | Healthcare | $1.15 | 3.60% | 0.70% | -0.05% | $10,775,656.00 |
| AVTX | Avalo Therapeutics, Inc. | NASDAQ | Healthcare | $8.39 | -1.87% | 2.25% | -2.21% | $68,198,257.00 |
| IBIO | iBio, Inc. | AMEX | Healthcare | $2.45 | -0.41% | -2.48% | 3.24% | $21,150,850.00 |
| XCUR | Exicure, Inc. | NASDAQ | Healthcare | $14.36 | -2.11% | 4.49% | 36.30% | $27,275,556.00 |
| FRTX | Fresh Tracks Therapeutics, Inc. | NASDAQ | Healthcare | $0.74 | 0.00% | 0.34% | 0.00% | $4,405,025.57 |
| ZEAL | Zealand Pharma A/S | NASDAQ | Healthcare | $0.00 | 0.00% | 0.00% | 0.00% | $0.00 |
